D-dopa
Sign in to saveAlso known as dopa D-form, (+)-3-(3,4-dihydroxyphenyl)alanine, (+)-3,4-dihydroxyphenylalanine, D-3-(3,4-dihydroxyphenyl)alanine, D-3,4-dihydroxyphenylalanine, 3-hydroxy-D-tyrosine, 3,4-dihydroxy-D-phenylalanine
-DOPA dextrodopa) is similar to (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's ability to rotate planes of polarized light in one or the other direction. Whereas is moderately effective in the treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain, is biologically inactive.
Wikidata facts
- Mass
- 197.068808
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- chemical formula
- C₉H₁₁NO₄
- isomeric SMILES
- C1=CC(=C(C=C1C[C@H](C(=O)O)N)O)O
- canonical SMILES
- C1=CC(=C(C=C1CC(C(=O)O)N)O)O
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-DOPA dextrodopa) is similar to (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's ability to rotate planes of polarized light in one or the other direction. Whereas is moderately effective in the treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain, is biologically inactive.
Avoiding unwanted production of D-DOPA is a goal for commercial synthesis of -based drugs to treat Parkinson's disease.