Also known as 2-Ala-4-mephe-5-gly-enkephalin, DAGO, glyol, Tyr-D-Ala-Gly-MePhe-Gly-ol, (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin
DAMGO ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin) is a synthetic opioid peptide with high μ-opioid receptor specificity. It was synthesized as a biologically stable analog of δ-opioid receptor-preferring endogenous opioids, leu- and met-enkephalin. Structures of DAMGO bound to the μ opioid receptor reveal a very similar binding pose to morphinans.
via PubMed
DAMGO ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin) is a synthetic opioid peptide with high μ-opioid receptor specificity. It was synthesized as a biologically stable analog of δ-opioid receptor-preferring endogenous opioids, leu- and met-enkephalin. Structures of DAMGO bound to the μ opioid receptor reveal a very similar binding pose to morphinans.
Its structure is H-Tyr-D-Ala-Gly-N-MePhe-Gly-ol.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).