dekstrorfan

Key facts

Drug.Verifiedfields

changed

Drug.Watchedfields

changed

Drug.verifiedrevid

408496712

Drug.IUPAC_name

(+)-17-methyl-9a,13a,14a-morphinan-3-ol

Drug.image

Dextrorphan.svg

Drug.image_class

skin-invert-image

Drug.legal_US

Unscheduled

Drug.CAS_number

125-73-5

Drug.ATC_prefix

None

Drug.PubChem

5360697

Drug.UNII

04B7QNO9WS

Drug.ChEMBL

1254766

Drug.ChemSpiderID

10489895

Drug.synonyms

DXO, Dextrorphanol

Drug.C

17

Drug.H

23

Drug.N

1

Drug.O

1

via Wikipedia infobox

Chemical data

Formula

C17H23NO

Molecular weight

257.37 g/mol

IUPAC name

(1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol

SMILES

CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)O

InChIKey

JAQUASYNZVUNQP-PVAVHDDUSA-N

XLogP

3.1

Polar surface area

23.5 Ų

H-bond donors

1

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• Neurotoxicity of dextrorphan.Archives of medical research · 1999
• Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity.Brain research · 1987
• Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers.Journal of clinical pharmacology · 2022
• Evaluating dextrorphan as a wastewater biomarker for cough suppressant use: A longitudinal study in China.Water research · 2025
• Dopamine enhancement of dextrorphan-induced skin antinociception in response to needle pinpricks in rats.Pharmacological reports : PR · 2019

via PubMed

Wikidata facts

Mass

257.177964

via Wikidata · CC0