DHPS

Name

deoxyhypusine synthase

Type

protein-coding

Position

12,673,411–12,681,901 (−)

Aliases

DHS, DS, MIG13, NEDSSWI

Ensembl

ENSG00000095059

RefSeq RNA

NM_001206974.2, NM_001369691.1, NM_001369692.1, NM_001369693.1, NM_001930.4

RefSeq protein

NP_001193903.1, NP_001356620.1, NP_001356621.1, NP_001356622.1, NP_001921.1

This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011].

via MyGene.info

Gene · Ensembl

deoxyhypusine synthase

Symbol

DHPS

Biotype

Protein coding

Organism

Homo sapiens

Location

19:12,673,411-12,681,901

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein DHPS PDB 1dhs.png

via Wikidata · CC0