diazoxide

Also known as Proglycem®, SCH-6783, SRG-95213, Diazossido, Diazoxidum, Eudemine, Diazoxido

Diazoxide, sold under the brand name Proglycem among others, is a medication used to treat low blood sugar due to a number of specific causes. This includes islet cell tumors that cannot be removed and leucine sensitivity. It can also be used in refractory cases of sulfonylurea toxicity. It is taken by mouth.

Chemical data

Formula: C8H7ClN2O2S
Molecular weight: 230.67 g/mol
IUPAC name: 7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
SMILES: CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
InChIKey: GDLBFKVLRPITMI-UHFFFAOYSA-N
XLogP: 1.2
Polar surface area: 66.9 Å²
H-bond donors: 1
H-bond acceptors: 3
Formal charge: 0

via PubChem

Research

4,572 papers

Diazoxide.

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Medical uses
Side effects
Research
References

Diazoxide, used as the salt diazoxide choline, and sold under the brand name Vykat XR, is used for the treatment of hyperphagia in people with Prader–Willi syndrome. It was approved for this use in the United States in March 2025.