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dienogest
EntityQ139160· pop 16· linked from 793 articles

dienogest

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Also known as dienogestrel, STS-557, (17-hydroxy-3-oxoestra-4,9-dien-17beta-yl)acetonitrile, BAY 86-5258, 17alpha-cyanomethyl-17beta-hydroxyestra-4,9(10)-dien-3-one, 17-alpha-cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one, 17alpha-17-hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile

Dienogest, sold under the brand name Visanne (manufactured by Bayer AG) among others, is a progestin medication which is used in birth control pills and in the treatment of endometriosis. It is also used in menopausal hormone therapy and to treat heavy periods. Dienogest is available both alone and in combination with estrogens. It is taken by mouth.

Key facts

Drug.C
20
Drug.H
25
Drug.N
1
Drug.O
2
Drug.Verifiedfields
verified
Drug.Watchedfields
verified
Drug.verifiedrevid
410941875
Drug.image
Dienogest.svg
Drug.image_class
skin-invert-image
Drug.width
225
Drug.image2
Dienogest molecule ball.png
Drug.image_class2
bg-transparent
Drug.width2
235
Drug.tradename
Visanne, others
Drug.pregnancy_AU
B3
Drug.routes_of_administration
By mouth
Drug.class
Progestogen; Progestin; Steroidal antiandrogen
Drug.ATC_prefix
G03

via Wikipedia infobox

Research

883 papers

via PubMed

Wikidata facts

Subclass of
progesterone congener
Mass
311.188529
Has use
medication
Show 6 more facts
chemical formula
C₂₀H₂₅NO₂
isomeric SMILES
C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(CC#N)O
canonical SMILES
CC12CCC3=C4CCC(=O)C=C4CCC3C1CCC2(CC#N)O
World Health Organisation international non-proprietary name
dienogest
defined daily dose
2
Commons category
Dienogest
Sources (4)

via Wikidata · CC0

~21 min read

Encyclopedic overview

27 sections
Contents
  • Medical uses
  • Birth control
  • Endometriosis
  • Heavy periods
  • Menopausal symptoms
  • Available forms
  • Contraindications
  • Side effects
  • Overdose
  • Interactions
  • Pharmacology
  • Pharmacodynamics
  • Progestogenic activity
  • Antigonadotropic effects
  • Antiandrogenic activity
  • Other activities
  • Pharmacokinetics
  • Chemistry
  • History
  • Society and culture
  • Generic names
  • Brand names
  • Availability
  • Research
  • References
  • Further reading
  • External links

Dienogest, sold under the brand name Visanne (manufactured by Bayer AG) among others, is a progestin medication which is used in birth control pills and in the treatment of endometriosis. It is also used in menopausal hormone therapy and to treat heavy periods. Dienogest is available both alone and in combination with estrogens. It is taken by mouth.

Side effects of dienogest include menstrual irregularities, headaches, nausea, breast tenderness, depression, and acne, among others. Dienogest is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It is a unique progestogen, with strong effects in the uterus. The medication has some antiandrogenic activity, which may help to improve androgen-dependent symptoms like acne, and has no other important hormonal activity.

Excerpted from Wikipedia’s “dienogest” article, available under the CC BY-SA 4.0 licence.

Gallery (2)

Available in 15 languages

via Wikidata sitelinks · CC0