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Structure via PubChem · Public domain (PubChem)
difetarsone
Sign in to saveDifetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection. It has also been used to treat Entamoeba histolytica infections.
Chemical data
- Formula
- C14H18As2N2O6
- Molecular weight
- 460.15 g/mol
- IUPAC name
- [4-[2-(4-arsonoanilino)ethylamino]phenyl]arsonic acid
- SMILES
- C1=CC(=CC=C1NCCNC2=CC=C(C=C2)[As](=O)(O)O)[As](=O)(O)O
- InChIKey
- YQVALJGIKVYRNI-UHFFFAOYSA-N
- Polar surface area
- 139 Ų
- H-bond donors
- 6
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- amebiasis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 459.96
Show 3 more facts
- chemical formula
- C₁₄H₁₈As₂N₂O₆
- Commons category
- Difetarsone
- canonical SMILES
- C1=CC(=CC=C1NCCNC2=CC=C(C=C2)[As](=O)(O)O)[As](=O)(O)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection. It has also been used to treat Entamoeba histolytica infections.
Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.
Excerpted from Wikipedia’s “difetarsone” article, available under the CC BY-SA 4.0 licence.