DKK3
Sign in to saveAlso known as REIC, RIG, dickkopf WNT signaling pathway inhibitor 3, CRRL
Dickkopf-related protein 3 is a protein in the Dickkopf family that in humans is encoded by the DKK3 gene.
Gene data
DKK3- Name
- dickkopf Wnt signaling pathway inhibitor 3
- Type
- protein-coding
- Aliases
- CRRL, REIC, RIG
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
dickkopf Wnt signaling pathway inhibitor 3
- Symbol
- DKK3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:11,956,207-12,009,948
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8303
- exact match
- identifiers.org/ncbigene/27122
- genomic end
- 12031316
- genomic start
- 11956207
- cytogenetic location
- 11p15.3
Sources (3)
via Wikidata · CC0
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- Further reading
Dickkopf-related protein 3 is a protein in the Dickkopf family that in humans is encoded by the DKK3 gene.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.