DVL1
Sign in to saveAlso known as DVL, DVL1L1, DVL1P1, DRS2, dishevelled segment polarity protein 1
Segment polarity protein dishevelled homolog DVL-1 is a protein that in humans is encoded by the DVL1 gene.
Gene data
DVL1- Name
- dishevelled segment polarity protein 1
- Type
- protein-coding
- Position
- 1,335,275–1,349,962 (−)
- Aliases
- DRS2, DVL, DVL1L1
- Ensembl
- ENSG00000107404
- RefSeq RNA
- NM_001330311.2, NM_004421.3, NM_181870.1, NM_182779.3, XM_005244732.5
- RefSeq protein
- NP_001317240.1, NP_004412.2, XP_005244789.1, XP_005244790.1, XP_047304046.1
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
dishevelled segment polarity protein 1
- Symbol
- DVL1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:1,335,275-1,349,962
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Segment polarity protein dishevelled homolog DVL-1 is a protein that in humans is encoded by the DVL1 gene.
== Function ==
Excerpted from Wikipedia’s “DVL1” article, available under the CC BY-SA 4.0 licence.