EIF4EBP2
Sign in to saveAlso known as 4EBP2, PHASII, eukaryotic translation initiation factor 4E binding protein 2
Eukaryotic translation initiation factor 4E-binding protein 2 is a protein that in humans is encoded by the EIF4EBP2 gene.
Gene data
EIF4EBP2- Name
- eukaryotic translation initiation factor 4E binding protein 2
- Type
- protein-coding
- Position
- 70,404,130–70,428,618 (+)
- Aliases
- 4EBP2, PHASII
- Ensembl
- ENSG00000148730
- RefSeq RNA
- NM_004096.5
- RefSeq protein
- NP_004087.1
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 4E binding protein 2
- Symbol
- EIF4EBP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:70,404,130-70,428,618
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3022
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1979
- genomic end
- 72188374
- genomic start
- 70404145
- chromosome
- human chromosome 10
- cytogenetic location
- 10q22.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Animal studies
- Interactions
- References
- Further reading
Eukaryotic translation initiation factor 4E-binding protein 2 is a protein that in humans is encoded by the EIF4EBP2 gene.
== Animal studies ==
Excerpted from Wikipedia’s “EIF4EBP2” article, available under the CC BY-SA 4.0 licence.