esculetin
Also known as 6,7-dihydroxycoumarin, aesculetin, cichorigenin, cichoriin aglucon, esculin aglycon, cichoriin aglycon, 6,7-dihydroxy-2H-1-benzopyran-2-one, esculin aglucon
Aesculetin (also known as esculetin, 6,7-dihydroxycoumarin and cichorigenin) is a derivative of coumarin. It is a natural lactone that derives from the intramolecular cyclization of a cinnamic acid derivative.
Chemical data
- Formula
- C9H6O4
- Molecular weight
- 178.14 g/mol
- IUPAC name
- 6,7-dihydroxychromen-2-one
via PubChem
Research
910 papers- Esculetin: A review of its pharmacology and pharmacokinetics.Phytotherapy research : PTR · 2022
- Esculetin unveiled: Decoding its anti-tumor potential through molecular mechanisms-A comprehensive review.Cancer reports (Hoboken, N.J.) · 2024
- Esculetin rebalances M1/M2 macrophage polarization to treat sepsis-induced acute lung injury through regulating metabolic reprogramming.Journal of cellular and molecular medicine · 2024
- Pharmacological and Therapeutic Applications of Esculetin.International journal of molecular sciences · 2022
- Esculetin inhibits liver cancer by targeting glucose-6-phosphate isomerase mediated glycolysis.
Article
2 sectionsContents
- See also
- References
Aesculetin (also known as esculetin, 6,7-dihydroxycoumarin and cichorigenin) is a derivative of coumarin. It is a natural lactone that derives from the intramolecular cyclization of a cinnamic acid derivative.
It is present in chicory and in many toxic and medicinal plants, in form of glycosides and caffeic acid conjugates.