etilefrine

Etilefrine, sold under the brand name Effortil among others, is a sympathomimetic medication used as an antihypotensive agent to treat orthostatic hypotension. It is usually used by mouth, but is also available as an injectable.

Research

307 papers

Etilefrine: A Novel Treatment for Refractory, Life-Threatening Chylothorax in the Newborn.Pediatrics · 2025
Etilefrine infusion for idiopathic chyle leakage in a critically ill child.Pediatrics international : official journal of the Japan Pediatric Society · 2022
Chylous Ascites: A Review of Pathogenesis, Diagnosis and Treatment.Journal of clinical and translational hepatology · 2018
Chylothorax.Thoracic surgery clinics · 2006
Refractory lymphorrhoea of the neck treated with etilefrine.European annals of otorhinolaryngology, head and neck diseases · 2021

via PubMed

Wikidata facts

Mass: 181.11

Show 4 more facts

chemical formula: C₁₀H₁₅NO₂
canonical SMILES: CCNCC(C1=CC(=CC=C1)O)O
Commons category: Etilefrine
defined daily dose: 50

Sources (3)

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Article

14 sections

Contents

Medical uses
Side effects
Pharmacology
Pharmacodynamics
Pharmacokinetics
Absorption
Distribution
Metabolism
Elimination
Chemistry
History
Society and culture
Names
References

Side effects of etilefrine include nausea, tremors, and palpitations, among others. Etilefrine is an agonist of the α- and β-adrenergic receptors. It is a substituted phenethylamine and is related to epinephrine, phenylephrine, and norfenefrine.