EXOC4
Sign in to saveAlso known as SEC8, SEC8L1, Sec8p, exocyst complex component 4
Exocyst complex component 4 is a protein that in humans is encoded by the EXOC4 gene.
Gene data
EXOC4- Name
- exocyst complex component 4
- Type
- protein-coding
- Position
- 133,253,054–134,067,137 (+)
- Aliases
- SEC8, SEC8L1, Sec8p
- Ensembl
- ENSG00000131558
- RefSeq RNA
- NM_001037126.2, NM_021807.4, XM_005250523.6, XM_017012494.3, XM_054358758.1
- RefSeq protein
- NP_001032203.1, NP_068579.3, XP_005250580.1, XP_016867983.1, XP_054214733.1
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
exocyst complex component 4
- Symbol
- EXOC4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:133,253,054-134,067,137
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Exocyst complex component 4 is a protein that in humans is encoded by the EXOC4 gene.
== Function ==
Excerpted from Wikipedia’s “EXOC4” article, available under the CC BY-SA 4.0 licence.