EXOC8

Name

exocyst complex component 8

Type

protein-coding

Position

231,332,753–231,337,852 (−)

Aliases

EXO84, Exo84p, NEDMISB, SEC84

Ensembl

ENSG00000116903

RefSeq RNA

NM_175876.5

RefSeq protein

NP_787072.2

This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016].