EXOC8
Sign in to saveAlso known as EXO84, Exo84p, SEC84, exocyst complex component 8, NEDMISB
Exocyst complex component 8 is a protein that in humans is encoded by the EXOC8 gene.
Gene data
EXOC8- Name
- exocyst complex component 8
- Type
- protein-coding
- Position
- 231,332,753–231,337,852 (−)
- Aliases
- EXO84, Exo84p, NEDMISB, SEC84
- Ensembl
- ENSG00000116903
- RefSeq RNA
- NM_175876.5
- RefSeq protein
- NP_787072.2
This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
exocyst complex component 8
- Symbol
- EXOC8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:231,332,753-231,337,852
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein EXOC8 PDB 1zc3.png
Show 5 more facts
- HomoloGene ID
- 44545
- exact match
- identifiers.org/ncbigene/149371
- genomic end
- 231473598
- genomic start
- 231468480
- cytogenetic location
- 1q42.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Exocyst complex component 8 is a protein that in humans is encoded by the EXOC8 gene.
== Interactions ==