FAT4
Sign in to saveAlso known as CDHF14, CDHR11, FAT-J, FATJ, NBLA00548, VMLDS2, HKLLS2, FAT atypical cadherin 4
Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.
Gene data
FAT4- Name
- FAT atypical cadherin 4
- Type
- protein-coding
- Aliases
- CDHF14, CDHR11, FAT-J, FATJ, HKLLS2, NBLA00548, VMLDS2
The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014].
via MyGene.info
Gene · Ensembl
FAT atypical cadherin 4
- Symbol
- FAT4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:125,314,918-125,492,932
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 14377
- exact match
- identifiers.org/ncbigene/79633
- genomic end
- 126414087
- genomic start
- 125314918
- cytogenetic location
- 4q28.1
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Clinical significance
- References
- Further reading
Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.
FAT4 is associated with the Hippo signaling pathway.