File:Cardiac_amyloidosis_very_high_mag_movat.jpg · Wikimedia Commons · See Wikimedia Commons
fibrosis
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Fibrosis, also known as fibrotic scarring, is the development of fibrous connective tissue in response to an injury. Fibrosis can be a normal connective tissue deposition or excessive tissue deposition caused by a disease.
Key facts
- Medical condition (new).name
- Fibrosis
- Medical condition (new).image
- Cardiac amyloidosis very high mag movat.jpg
- Medical condition (new).caption
- Micrograph of a heart showing fibrosis (yellow – left of image) and amyloid deposition (brown – right of image). Stained using Movat's stain.
- Medical condition (new).field
- Pathology, rheumatology
- Medical condition (new).complications
- Cirrhosis
- Medical condition (new).risks
- Repeated injuries, chronic inflammation.
via Wikipedia infobox
Research
448,277 papers- Pulmonary fibrosis: patterns and perpetrators.The Journal of clinical investigation · 2012
- Myocardial fibrosis.Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 2018
- Progressive Pulmonary Fibrosis: Current Status in Terminology and Future Directions.Advances in therapy · 2025
- Gadolinium-Induced Fibrosis.Annual review of medicine · 2016
- Cellular Senescence in Lung Fibrosis.International journal of molecular sciences · 2021
via PubMed
Wikidata facts
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- Commons category
- Fibrosis
via Wikidata · CC0
~6 min read
Article
10 sectionsContents
- Physiology
- Anatomical location
- Lungs
- Liver
- Kidney
- Brain
- Heart
- Other
- References
- External links
Fibrosis, also known as fibrotic scarring, is the development of fibrous connective tissue in response to an injury. Fibrosis can be a normal connective tissue deposition or excessive tissue deposition caused by a disease.
Repeated injuries, chronic inflammation and repair are susceptible to fibrosis, where an accidental excessive accumulation of extracellular matrix components, such as collagen, is produced by fibroblasts, leading to the formation of a permanent fibrotic scar.