Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Within Vinony's link graph, flufenamic acid is referenced by 1,706 other articles, and connects out to valproic acid, salicylic acid and barbiturates.
Vinony files it under 3-(Trifluoromethyl)phenyl compounds, Anthranilic acids and Drugboxes which contain changes to watched fields.
Its subject is documented across 13 Wikipedia language editions.
Chemical data
- Formula
- C14H10F3NO2
- Molecular weight
- 281.23 g/mol
- IUPAC name
- 2-[3-(trifluoromethyl)anilino]benzoic acid
- SMILES
- C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F
- InChIKey
- LPEPZBJOKDYZAD-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 49.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- rheumatic disease
via ChEMBL · EBI
Research
1,643 papers- Flufenamic acid as an ion channel modulator.Pharmacology & therapeutics · 2013
- Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.Journal of neuroinflammation · 2022
- Flufenamic acid resensitizes MRSA to gentamicin through synergistic ion modulation.The Journal of antimicrobial chemotherapy · 2026
- Flufenamic acid inhibits osteoclast formation and bone resorption and act against estrogen-dependent bone loss in mice.International immunopharmacology · 2020
- Antibacterial and antibiofilm effects of flufenamic acid against methicillin-resistant Staphylococcus aureus.Pharmacological research · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 281.066
Show 7 more facts
- chemical formula
- C₁₄H₁₀F₃NO₂
- canonical SMILES
- C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F
- subject has role
- anti-inflammatory agent
- melting point
- 134
- World Health Organisation international non-proprietary name
- flufenamic acid
- has characteristic
- bitterness
- Commons category
- Flufenamic acid
via Wikidata · CC0
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