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flunitrazepam

Structure via PubChem · Public domain (PubChem)

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flunitrazepam

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Flunitrazepam, sold under the brand name Rohypnol among others, is a benzodiazepine used to treat severe insomnia and assist with anesthesia. As with other hypnotics, flunitrazepam has been advised to be prescribed only for short-term use or by those with chronic insomnia on an occasional basis.

Key facts

Drug.Watchedfields
changed
Drug.class
Benzodiazepine
Drug.verifiedrevid
477167367
Drug.IUPAC_name
5-(2-fluorophenyl)-1-methyl-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
Drug.image
Flunitrazepam structure.svg
Drug.image_class
skin-invert-image
Drug.width
200
Drug.image2
Flunitrazepam-from-xtal-3D-balls.png
Drug.image_class2
bg-transparent
Drug.tradename
Rohypnol
Drug.pregnancy_AU
C
Drug.legal_AU
S8
Drug.legal_BR
B1
Drug.legal_CA
Schedule I
Drug.legal_DE
Anlage III
Drug.legal_UK
Class C
Drug.legal_US
Schedule IV (Schedule I trafficking penalties, however)
Drug.legal_UN
Psychotropic Schedule III

via Wikipedia infobox

Chemical data

Formula
C16H12FN3O3
Molecular weight
313.28 g/mol
IUPAC name
5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
SMILES
CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
InChIKey
PPTYJKAXVCCBDU-UHFFFAOYSA-N
XLogP
2.1
Polar surface area
78.5 Ų
H-bond donors
0
H-bond acceptors
5
Formal charge
0

via PubChem

Research

3,840 papers

via PubMed

Wikidata facts

Mass
313.086269
Show 6 more facts
Commons category
Flunitrazepam
chemical formula
C₁₆H₁₂FN₃O₃
World Health Organisation international non-proprietary name
flunitrazepam
canonical SMILES
CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
defined daily dose
1
MCN code
2933.91.32
Sources (4)

via Wikidata · CC0

~15 min read

Article

23 sections
Contents
  • Use
  • Adverse effects
  • Dependence
  • Paradoxical effects
  • Hypotonia
  • Other
  • Special precautions
  • Interactions
  • Overdose
  • Detection
  • Pharmacology
  • Chemistry
  • History
  • Society and culture
  • Recreational and illegal uses
  • Recreational use
  • Suicide
  • Drug-facilitated sexual assault
  • Drug-facilitated robbery
  • Regional use
  • Names
  • References
  • External links

Flunitrazepam, sold under the brand name Rohypnol among others, is a benzodiazepine used to treat severe insomnia and assist with anesthesia. As with other hypnotics, flunitrazepam has been advised to be prescribed only for short-term use or by those with chronic insomnia on an occasional basis.

Flunitrazepam was patented in 1962 and came into medical use in 1974. Nicknamed "roofies" or "floonies", it is widely known for its use as a date rape drug.

Gallery (9)

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