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tasimelteon

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Also known as BMS-214778, Hetlioz®, VEC-162, VEC 162, BMS 214778, tasimeltéon, N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide

Tasimelteon, sold under the brand name Hetlioz, is a medication approved by the U.S. Food and Drug Administration (FDA) in January 2014, for the treatment of non-24-hour sleep–wake disorder (also called non-24, N24 and N24HSWD). In June 2014, the European Medicines Agency (EMA) accepted an EU filing application for tasimelteon and in July 2015, the drug was approved in the European Union for the treatment of non-24-hour sleep-wake rhythm disorder in totally blind adults, but not in the case of non-24 in sighted people.

Wikidata facts

Mass
245.141579
Show 5 more facts
chemical formula
C₁₅H₁₉NO₂
canonical SMILES
CCC(=O)NCC1CC1C2=C3CCOC3=CC=C2
isomeric SMILES
CCC(=O)NC[C@@H]1C[C@H]1C2=C3CCOC3=CC=C2
World Health Organisation international non-proprietary name
tasimelteon
Commons category
Tasimelteon
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Article

7 sections
Contents
  • Medical uses
  • Development
  • FDA approval
  • Toxicity
  • See also
  • References
  • External links

Tasimelteon, sold under the brand name Hetlioz, is a medication approved by the U.S. Food and Drug Administration (FDA) in January 2014, for the treatment of non-24-hour sleep–wake disorder (also called non-24, N24 and N24HSWD). In June 2014, the European Medicines Agency (EMA) accepted an EU filing application for tasimelteon and in July 2015, the drug was approved in the European Union for the treatment of non-24-hour sleep-wake rhythm disorder in totally blind adults, but not in the case of non-24 in sighted people.

The most common side effects include headache, somnolence, nausea (feeling sick) and dizziness.

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