chloralose

Chloralose (also known as α-chloralose) is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative. Either alone or in combination, such as with urethane, it is used for long-lasting, but light anesthesia. It has been used with oral administration to sedate wild Canada geese for translocation in Nevada.

In the Vinony graph

Within Vinony's link graph, chloralose is referenced by 794 other articles, and connects out to benzodiazepine drug, allopregnanolone and isovaleric acid.

It sits within the topics Acetals, Avicides and Chembox having GHS data.

Its subject is documented across 12 Wikipedia language editions.

Chemical data

Formula: C8H11Cl3O6
Molecular weight: 309.5 g/mol
IUPAC name: (1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol
SMILES: C([C@H]([C@@H]1[C@@H]([C@@H]2[C@H](O1)O[C@@H](O2)C(Cl)(Cl)Cl)O)O)O
InChIKey: OJYGBLRPYBAHRT-IPQSZEQASA-N
XLogP: 1
Polar surface area: 88.4 Å²
H-bond donors: 3
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Research

5,580 papers

The pharmacology of chloralose. A review.Psychopharmacologia · 1964
[Alpha-chloralose].Tijdschrift voor diergeneeskunde · 1992
Alpha-chloralose as a canine anesthetic.Laboratory animal science · 1987
Pharmacology and toxicology of alpha chloralose: a review.The Veterinary record · 1972
A review of laboratory animal anesthesia with chloral hydrate and chloralose.Laboratory animal science · 1993

via PubMed

Wikidata facts

Mass: 307.962
Has use: rodenticide

Show 5 more facts

melting point: 183
chemical formula: C₈H₁₁Cl₃O₆
Commons category: Chloralose
canonical SMILES: C(C(C1C(C2C(O1)OC(O2)C(Cl)(Cl)Cl)O)O)O
isomeric SMILES: C([C@H]([C@@H]1[C@@H]([C@@H]2[C@H](O1)O[C@@H](O2)C(Cl)(Cl)Cl)O)O)O

Sources (3)

via Wikidata · CC0

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