File:Gallstones.png · Wikimedia Commons · See Wikimedia Commons
gallstone disease
Sign in to saveAlso known as gallstones, cholelithiasis
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AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Medical condition (new).name
- Gallstone
- Medical condition (new).image
- Gallstones.png
- Medical condition (new).caption
- Gallstones typically form in the gallbladder and may result in symptoms if they block the biliary system.
- Medical condition (new).field
- GastroenterologyGeneral surgery
- Medical condition (new).pronounce
- Cholelith , cholelithiasis
- Medical condition (new).synonyms
- Gallstone disease, cholelith, cholecystolithiasis (gallstone in the gallbladder), choledocholithiasis (gallstone in a bile duct)
- Medical condition (new).symptoms
- None, crampy pain in the right upper abdomen
- Medical condition (new).complications
- Inflammation of the gallbladder, inflammation of the pancreas, liver inflammation
- Medical condition (new).onset
- After 40 years old
- Medical condition (new).risks
- Birth control pills, pregnancy, family history, obesity, diabetes, liver disease, rapid weight loss
- Medical condition (new).diagnosis
- Based on symptoms and physical examination , confirmed by ultrasound
- Medical condition (new).prevention
- Healthy weight, diet high in fiber, diet low in simple carbohydrates
- Medical condition (new).treatment
- Asymptomatic: none, ursodeoxycholic acid (UDCA) and Chenodeoxycholic acid Pain: surgery ERCP, Cholecystectomy
- Medical condition (new).prognosis
- Good after surgery
- Medical condition (new).frequency
- 10–15% of adults (developed world)
via Wikipedia infobox
Research
44,590 papers- The Treatment of Gallstone Disease.ReviewDeutsches Arzteblatt international · 2020Gutt C, Schläfer S, Lammert FDOI: 10.3238/arztebl.2020.0148
- Management of Gallstone Disease.ReviewThe Surgical clinics of North America · 2024Liepert AE, Ancheta M, Williamson EDOI: 10.1016/j.suc.2024.04.015
- An update on the pathogenesis of cholesterol gallstone disease.ReviewCurrent opinion in gastroenterology · 2018Di Ciaula A, Wang DQ, Portincasa PDOI: 10.1097/MOG.0000000000000423
- Genetics of gallstone disease.ReviewEuropean journal of clinical investigation · 2018Rebholz C, Krawczyk M, Lammert FDOI: 10.1111/eci.12935
- Factors Influencing Gallstone Formation: A Review of the Literature.ReviewBiomolecules · 2022Sun H, Warren J, Yip J et al.DOI: 10.3390/biom12040550
- Mouse models of gallstone disease.ReviewCurrent opinion in gastroenterology · 2018Wang TY, Portincasa P, Liu M et al.DOI: 10.1097/MOG.0000000000000417
- Gallstone disease: Microlithiasis and sludge.ReviewBest practice & research. Clinical gastroenterology · 2006Jüngst C, Kullak-Ublick GA, Jüngst DDOI: 10.1016/j.bpg.2006.03.007
- Pathophysiological connections between gallstone disease, insulin resistance, and obesity.ReviewObesity reviews : an official journal of the International Association for the Study of Obesity · 2020Cortés VA, Barrera F, Nervi FDOI: 10.1111/obr.12983
via PubMed
~19 min read
Encyclopedic overview
26 sectionsContents
- Definition
- Signs and symptoms
- Biliary colic
- Complications
- Acute cholecystitis
- Choledocholithiasis
- Ascending cholangitis
- Gallstone (biliary) pancreatitis
- Gallstone ileus
- Cancer
- Risk factors
- Pathophysiology
- Composition
- Cholesterol stones
- Pigment stones
- Mixed stones
- Diagnosis
- Prevention
- Treatment
- Lithotripsy
- Surgical
- Medical
- Use in alternative medicine
- See also
- References
- External links
A gallstone is a stone formed within the gallbladder from precipitated bile components. The term cholelithiasis may refer to the presence of gallstones or to any disease caused by gallstones, and choledocholithiasis refers to the presence of migrated gallstones within bile ducts.
Most people with gallstones (about 80%) are asymptomatic. However, when a gallstone obstructs the bile duct and causes acute cholestasis, a reflexive smooth muscle spasm often occurs, resulting in an intense cramp-like visceral pain in the right upper part of the abdomen known as a biliary colic (or "gallbladder attack"). This happens in 1–4% of those with gallstones each year. Complications from gallstones may include inflammation of the gallbladder (cholecystitis), inflammation of the pancreas (pancreatitis), obstructive jaundice, and infection in bile ducts (cholangitis). Symptoms of these complications may include pain that lasts longer than five hours, fever, yellowish skin, vomiting, dark urine, and pale stools.
Excerpted from Wikipedia’s “gallstone disease” article, available under the CC BY-SA 4.0 licence.