Structure via PubChem · Public domain (PubChem)
garenoxacin
Sign in to saveAlso known as T-3811, T 3811, BMS-284756, BMS284756, BMS 284756, desquinolone
Garenoxacin (INN) is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections.
In the Vinony graph
Vinony's link graph records 116 inbound references to garenoxacin, and connects out to sulfamethazine, antibiotic and fidaxomicin.
It sits within the topics Carboxylic acids, Chemical pages without DrugBank identifier and Cyclopropyl compounds.
Vinony links it to 8 Wikipedia language editions.
Chemical data
- Formula
- C23H20F2N2O4
- Molecular weight
- 426.4 g/mol
- IUPAC name
- 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxoquinoline-3-carboxylic acid
- SMILES
- C[C@@H]1C2=C(CN1)C=C(C=C2)C3=C(C4=C(C=C3)C(=O)C(=CN4C5CC5)C(=O)O)OC(F)F
- InChIKey
- NJDRXTDGYFKORP-LLVKDONJSA-N
- XLogP
- 2.1
- Polar surface area
- 78.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2007
- Indications
- bacterial disease
via ChEMBL · EBI
Research
290 papers- Clinical studies of garenoxacin.International journal of antimicrobial agents · 2008
- Garenoxacin.The Journal of the Association of Physicians of India · 2014
- Garenoxacin pharmacokinetics in subjects with renal impairment.Current medical research and opinion · 2007
- Garenoxacin pharmacokinetics in patients undergoing maintenance hemodialysis.Hemodialysis international. International Symposium on Home Hemodialysis · 2017
- The clinical efficacy of garenoxacin for male non-gonococcal urethritis.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2020
via PubMed
Wikidata facts
- Mass
- 426.139
- Has use
- medication
Show 4 more facts
- chemical formula
- C₂₃H₂₀F₂N₂O₄
- canonical SMILES
- CC1C2=C(CN1)C=C(C=C2)C3=C(C4=C(C=C3)C(=O)C(=CN4C5CC5)C(=O)O)OC(F)F
- isomeric SMILES
- C[C@@H]1C2=C(CN1)C=C(C=C2)C3=C(C4=C(C=C3)C(=O)C(=CN4C5CC5)C(=O)O)OC(F)F
- World Health Organisation international non-proprietary name
- garenoxacin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Garenoxacin (INN) is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections.
Garenoxacin was discovered by Toyama Chemical Co., Ltd. of Tokyo, Japan, and is currently being marketed in Japan under the tradename Geninax. Schering-Plough holds worldwide rights for garenoxacin, except for Japan, South Korea, and China.
Excerpted from Wikipedia’s “garenoxacin” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0