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temafloxacin

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Also known as Temafloxacina, Temafloxacine, Temafloxacinum

Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths. It is not marketed in Europe.

Research

275 papers

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Wikidata facts

Mass
417.130026
Has use
medication
Show 5 more facts
chemical formula
C₂₁H₁₈F₃N₃O₃
subject has role
antibiotic
canonical SMILES
CC1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=C(C=C(C=C4)F)F)F
defined daily dose
0.8
Commons category
Temafloxacin
Sources (3)

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Encyclopedic overview

6 sections
Contents
  • History
  • Pharmacokinetics
  • Clinical uses
  • See also
  • References
  • External links

Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths. It is not marketed in Europe.

== History == Omniflox was approved to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections in the United States by the Food and Drug Administration in January 1992. Severe adverse reactions, including allergic reactions and hemolytic anemia, developed in over 100 patients during the first four months of its use, leading to three patient deaths. Abbott withdrew the drug from sale in June 1992.

Excerpted from Wikipedia’s “temafloxacin” article, available under the CC BY-SA 4.0 licence.