GATAD2B
Sign in to saveAlso known as MRD18, P66beta, p68, GATA zinc finger domain containing 2B, GANDS
Transcriptional repressor p66-beta is a protein that in humans is encoded by the GATAD2B gene.
Gene data
GATAD2B- Name
- GATA zinc finger domain containing 2B
- Type
- protein-coding
- Position
- 153,789,030–153,923,360 (−)
- Aliases
- GANDS, MRD18, P66beta, p68
- Ensembl
- ENSG00000261992
- RefSeq RNA
- NM_020699.4, XM_047426115.1, XM_047426117.1, XM_054337814.1, XM_054337815.1
- RefSeq protein
- NP_065750.1, XP_047282071.1, XP_047282073.1, XP_054193789.1, XP_054193790.1
This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with cognitive disability. [provided by RefSeq, Jun 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
GATA zinc finger domain containing 2B
- Symbol
- GATAD2B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:153,789,030-153,923,360
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Transcriptional repressor p66-beta is a protein that in humans is encoded by the GATAD2B gene.
==Interactions== GATAD2B has been shown to interact with Methyl-CpG-binding domain protein 2, MBD3, RBBP7 and RBBP4.
Excerpted from Wikipedia’s “GATAD2B” article, available under the CC BY-SA 4.0 licence.
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