RBBP7
Sign in to saveAlso known as RbAp46, retinoblastoma binding protein 7, RB binding protein 7, chromatin remodeling factor
Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene.
Gene data
RBBP7- Name
- RB binding protein 7, chromatin remodeling factor
- Type
- protein-coding
- Chromosome
- X
- Position
- 16,838,236–16,870,415 (−)
- Aliases
- RbAp46, SPGFX9
- Ensembl
- ENSG00000102054
- RefSeq RNA
- NM_001198719.2, NM_002893.4, XM_047442291.1, XM_047442292.1, XM_054327469.1
- RefSeq protein
- NP_001185648.1, NP_002884.1, XP_047298247.1, XP_047298248.1, XP_054183444.1
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RB binding protein 7, chromatin remodeling factor
- Symbol
- RBBP7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:16,838,236-16,870,415
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene.
== Function ==
Excerpted from Wikipedia’s “RBBP7” article, available under the CC BY-SA 4.0 licence.