H4C1

Also known as H4FA, histone cluster 1, H4a, histone cluster 1 H4 family member a, HIST1H4A, H4 clustered histone 1, H4C5, H4C4, H4C9

Histone H4 is a protein that in humans is encoded by the HIST1H4A gene.

In the Vinony graph

Within Vinony's link graph, H4C1 is referenced by 3 other articles, and connects out to PubMed, Ensembl genome database project and protein.

Vinony files it under Genes on human chromosome 6 and Human proteins.

Its subject is documented across 5 Wikipedia language editions.

Gene data

H4C1

Name: H4 clustered histone 1
Type: protein-coding
Position: 26,021,649–26,022,847 (+)
Aliases: H4FA, HIST1H4A
Ensembl: ENSG00000278637
RefSeq RNA: NM_003538.4
RefSeq protein: NP_003529.1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].

Pathways

Neutrophil extracellular trap formation - Homo sapiens (human)Alcoholism - Homo sapiens (human)Viral carcinogenesis - Homo sapiens (human)Systemic lupus erythematosus - Homo sapiens (human)Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine

via MyGene.info

Gene · Ensembl

H4 clustered histone 1

Symbol: H4C1
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:26,021,649-26,022,847
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 134481
chromosome: human chromosome 6
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/8359
genomic start: 26021649
genomic end: 26022050
cytogenetic location: 6p22.2
expressed in: granulocyte

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
Further reading
External links

Histone H4 is a protein that in humans is encoded by the HIST1H4A gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Excerpted from Wikipedia’s “H4C1” article, available under the CC BY-SA 4.0 licence.