H1-2

Also known as H1.2, H1C, H1F2, H1s-1, histone cluster 1, H1c, histone cluster 1 H1 family member c, HIST1H1C, H1.2 linker histone, cluster member

Histone H1.2 is a protein that in humans is encoded by the HIST1H1C gene.

Gene data

H1-2

Name: H1.2 linker histone, cluster member
Type: protein-coding
Aliases: H1.2, H1C, H1F2, H1s-1, HIST1H1C

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].

via MyGene.info

Gene · Ensembl

H1.2 linker histone, cluster member

Symbol: H1-2
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:26,054,760-26,056,470
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 68455
exact match: identifiers.org/ncbigene/3006
genomic end: 26056470
genomic start: 26055740
cytogenetic location: 6p22.2

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Histone H1.2 is a protein that in humans is encoded by the HIST1H1C gene.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.