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GeneQ18049232· pop 5· linked from 99 articles

GRIN3A

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Also known as GluN3A, NMDAR-L, NR3A, glutamate ionotropic receptor NMDA type subunit 3A, NMDAR3A

Glutamate [NMDA] receptor subunit 3A is a protein that in humans is encoded by the GRIN3A gene.

Gene data

GRIN3A
Name
glutamate ionotropic receptor NMDA type subunit 3A
Type
protein-coding
Position
101,569,352–101,738,654 (−)
Aliases
GluN3A, NMDAR-L, NMDAR3A, NR3A
Ensembl
ENSG00000198785
RefSeq RNA
NM_133445.3, XM_011518211.3, XM_054361948.1
RefSeq protein
NP_597702.2, XP_011516513.1, XP_054217923.1

This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Spinocerebellar ataxia - Homo sapiens (human)Prion disease - Homo sapiens (human)Cocaine addiction - Homo sapiens (human)Amphetamine addiction - Homo sapiens (human)Nicotine addiction - Homo sapiens (human)Alcoholism - Homo sapiens (human)Neurotransmitter receptors and postsynaptic signal transmission

via MyGene.info

Gene · Ensembl

glutamate ionotropic receptor NMDA type subunit 3A

Symbol
GRIN3A
Biotype
Protein coding
Organism
Homo sapiens
Location
9:101,569,352-101,738,654
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
128613
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/116443
genomic end
101738647
genomic start
101569352
chromosome
human chromosome 9
cytogenetic location
9q31.1
expressed in
anterior cingulate cortex
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • See also
  • References
  • Further reading
  • External links

Glutamate [NMDA] receptor subunit 3A is a protein that in humans is encoded by the GRIN3A gene.

== Function ==

Excerpted from Wikipedia’s “GRIN3A” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0