هارمین

Also known as 7-methoxy-1-methyl-9H-beta-carboline, 6-methoxyharman, yageine, banisterine, yajeine, leucoharmine, telepathine

Harmine, also known as banisterine or telepathine, as well as 7-methoxyharman or 7-methoxy-1-methyl-β-carboline, is a β-carboline and a harmala alkaloid which has hallucinogenic effects and monoamine oxidase inhibitor (MAOI) activity. It occurs in a number of different plants, most notably Peganum harmala and Banisteriopsis caapi. Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a reversible inhibitor of monoamine oxidase A (RIMA). Harmine does not inhibit MAO-B.

Key facts

Drug.Watchedfields: verified
Drug.verifiedrevid: 443852670
Drug.image: Harmine structure.svg
Drug.image_class: skin-invert-image
Drug.width: 225px
Drug.image2: Harmine_3d_structure.png
Drug.image_class2: bg-transparent
Drug.width2: 225px
Drug.routes_of_administration: Oral, sublingual, subcutaneous injection, intramuscular injection, intravenous injection
Drug.class: Hallucinogen; Oneirogen; Monoamine oxidase inhibitor; Reversible inhibitor of MAO-A
Drug.ATC_prefix: None
Drug.onset: Unknown
Drug.elimination_half life: 1.3–1.9 hours (1–3 hours)
Drug.duration_of_action: Oral: 6–8 hours: 3–5 hours: 30–45 minutes
Drug.CAS_number: 442-51-3
Drug.PubChem: 5280953
Drug.DrugBank: DB07919
Drug.ChemSpiderID: 4444445

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Research

1,503 papers

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Wikidata facts

Has part: carbon
Mass: 212.095

Show 8 more facts

found in taxon: Grewia damine
canonical SMILES: CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
chemical formula: C₁₃H₁₂N₂O
subject has role: entheogen
melting point: 273
Commons category: Harmine
decomposition point: 261
pKa: 7.70

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