Also known as HEL-S-28, ILK-1, ILK-2, P59, p59ILK, integrin linked kinase
protein-coding gene in the species Homo sapiens
Gene data
ILK- Name
- integrin linked kinase
- Type
- protein-coding
- Aliases
- HEL-S-28, ILK-1, ILK-2, P59, p59ILK
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].
via MyGene.info
Gene · Ensembl
integrin linked kinase
- Symbol
- ILK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:6,603,708-6,610,874
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein ILK PDB 2KBX.png
Show 5 more facts
- HomoloGene ID
- 3318
- exact match
- identifiers.org/ncbigene/3611
- genomic end
- 6632102
- genomic start
- 6624961
- cytogenetic location
- 11p15.4
via Wikidata · CC0
Connections
Q180686
Entity
integrins
Entity
Ensembl genome database project
Entity
enzyme
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Wikidata
Entity
gene
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chromosome
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digital object identifier
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International Standard Serial Number
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cytoplasm
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bibcode
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human genome
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Q229883
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base pair
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locus
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centrosome
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gene expression
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Online Mendelian Inheritance in Man
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extracellular matrix
Entity
kinase
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