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immunodeficiency

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Also known as Immunologic Deficiency Syndrome, Immunologic Deficiency Syndromes, immune deficiency

Immunodeficiency, also known as immunocompromise, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection and environmental factors, such as nutrition. Immunocompromisation may also be due to genetic diseases/flaws such as SCID.

In the Vinony graph

Vinony's link graph records 1,098 inbound references to immunodeficiency, and connects out to HIV/AIDS, granulocyte and infection.

It is catalogued under the topic Immunodeficiency.

Vinony links it to 40 Wikipedia language editions.

Key facts

Medical condition (new).name
Immunodeficiency
Medical condition (new).field
Immunology
Medical condition (new).synonyms
Immunocompromise, immune deficiency, immunocompromisation
Medical condition (new).medication
Imuran

via Wikipedia infobox

Research

474,824 papers

via PubMed

Wikidata facts

Show 2 more facts
Commons category
Immunodeficiencies
NCI Thesaurus ID
C39725
Sources (4)

via Wikidata · CC0

~16 min read

Encyclopedic overview

16 sections
Contents
  • Types
  • By affected component
  • Primary or secondary
  • Primary immunodeficiency
  • Secondary immunodeficiencies
  • Causes
  • Immunodeficiency and autoimmunity
  • Antibody vulnerability period in children
  • Classes of immunoglobulins (Igs)
  • Immunoglobulin Subclasses and Their Properties
  • Diagnosis
  • Treatment
  • Prognosis
  • See also
  • References
  • External links

Immunodeficiency, also known as immunocompromise, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection and environmental factors, such as nutrition. Immunocompromisation may also be due to genetic diseases/flaws such as SCID.

In clinical settings, immunosuppression by some drugs, such as steroids, can either be an adverse effect or the intended purpose of the treatment. Examples of such use include organ transplant surgery as an anti-rejection measure and in patients with an overactive immune system, such as in autoimmune diseases. Some people are born with intrinsic defects in their immune system, or primary immunodeficiency.

Excerpted from Wikipedia’s “immunodeficiency” article, available under the CC BY-SA 4.0 licence.

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