File:Neutrophil_with_anthrax_copy.jpg · Wikimedia Commons · See Wikimedia Commons
phagocyte
Sign in to saveAlso known as phagocytes, Phagocytic cell
thumb|Scanning electron microscope|Scanning electron micrograph of a neutrophil phagocytosing anthrax bacilli (orange)|alt= Long rod-shaped bacteria, one of which has been partially engulfed by a larger blob-shaped white blood cell. The shape of the cell is distorted by undigested bacterium inside it.
A phagocyte is a type of white blood cell that protects the body by engulfing and destroying harmful invaders like bacteria. In the image shown, you can see a neutrophil (a common phagocyte) in the process of consuming anthrax bacteria, demonstrating how these cells actively patrol the body to eliminate threats to health.
AI-generated from the Wikipedia summary — may contain errors.
Research
392,567 papers- Phagocyte Responses to Cell Death in Flies.ReviewCold Spring Harbor perspectives in biology · 2020Davidson AJ, Wood WDOI: 10.1101/cshperspect.a036350
- Disorders of phagocyte chemotaxis.ReviewAnnals of internal medicine · 1980Gallin JI, Wright DG, Malech HL et al.DOI: 10.7326/0003-4819-92-4-520
- Modern management of phagocyte defects.ReviewPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2017Lanini LL, Prader S, Siler U et al.DOI: 10.1111/pai.12654
- Phagocyte-myocyte interactions and consequences during hypoxic wound healing.ReviewCellular immunology · 2014Zhang S, Dehn S, DeBerge M et al.DOI: 10.1016/j.cellimm.2014.04.006
- Phagocyte partnership during the onset and resolution of inflammation.ReviewNature reviews. Immunology · 2010Soehnlein O, Lindbom LDOI: 10.1038/nri2779
- Assembly of the phagocyte NADPH oxidase.ReviewHistochemistry and cell biology · 2004Nauseef WMDOI: 10.1007/s00418-004-0679-8
- Phagocyte uptake and transport of azithromycin.ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1991McDonald PJ, Pruul HDOI: 10.1007/BF01975835
- Modulation of phagocyte apoptosis by bacterial pathogens.ReviewApoptosis : an international journal on programmed cell death · 2004DeLeo FRDOI: 10.1023/B:APPT.0000031448.64969.fa
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~39 min read
Article
31 sectionsContents
- History
- Phagocytosis
- Methods of killing
- Oxygen-dependent intracellular
- Oxygen-independent intracellular
- Extracellular
- Viruses
- Role in apoptosis
- Interactions with other cells
- Antigen presentation
- Immunological tolerance
- Professional phagocytes
- Activation
- Migration
- Monocytes
- Macrophages
- Neutrophils
- Dendritic cells
- Mast cells
- Non-professional phagocytes
- Pathogen evasion and resistance
- Avoiding contact
- Avoiding engulfment
- Survival inside the phagocyte
- Killing
- Disruption of cell signaling
- Host damage by phagocytes
- Evolutionary origins
- References
- Bibliography
- External links
thumb|Scanning electron microscope|Scanning electron micrograph of a neutrophil phagocytosing anthrax bacilli (orange)|alt= Long rod-shaped bacteria, one of which has been partially engulfed by a larger blob-shaped white blood cell. The shape of the cell is distorted by undigested bacterium inside it.
Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells. They include monocytes, macrophages, neutrophils, tissue dendritic cells, and mast cells. Their name comes from the Greek '', "to eat" or "devour", and "-cyte", the suffix in biology denoting "cell", from the Greek kutos, "hollow vessel". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life. Discovered in 2019, species of bacteria Candidatus'' Uabimicrobium amorphum can perform phagocytosis by eating other bacteria.