multiple sclerosis

Also known as MS, encephalomyelitis disseminata, insular sclerosis, disseminated sclerosis, generalized multiple sclerosis

disease that damages the myelin sheaths around nerve axons

AI overview

Multiple sclerosis is a disease where the body's immune system damages the protective coating (called myelin) around nerve fibers, which disrupts communication between the brain and the rest of the body. It matters because this damage can lead to a range of physical and cognitive symptoms that affect a person's ability to move, see, and think clearly.

AI-generated from the Wikipedia summary — may contain errors.

Research

127,009 papers

Progressive multiple sclerosis: from pathogenic mechanisms to treatment.ReviewBrain : a journal of neurology · 2017Correale J, Gaitán MI, Ysrraelit MC et al.DOI: 10.1093/brain/aww258
Multiple sclerosis.Biomedical journal · 2014Wei FCDOI: 10.4103/2319-4170.130317
Multiple sclerosis under the spotlight.The Lancet. Neurology · 2021The Lancet NeurologyDOI: 10.1016/S1474-4422(21)00170-8
Multiple sclerosis.Nature · 2016Owens BDOI: 10.1038/540S1a
Pediatric Multiple Sclerosis: A Review.ReviewAdvances in pediatrics · 2019Langille MM, Rutatangwa A, Francisco CDOI: 10.1016/j.yapd.2019.03.003
Pathophysiology, Diagnosis, Treatment and Emerging Neurotherapeutic Targets for Progressive Multiple Sclerosis: The Age of PIRA.ReviewNeurologic clinics · 2024Carlson AK, Fox RJDOI: 10.1016/j.ncl.2023.07.002
Multiple sclerosis.Nature · 2012Brody HDOI: 10.1038/nature11104
Multiple Sclerosis: Basic and Clinical.ReviewAdvances in neurobiology · 2017Buzzard K, Chan WH, Kilpatrick T et al.DOI: 10.1007/978-3-319-57193-5_8

via PubMed

Wikidata facts

Image: MS Demyelinisation CD68 10xv2.jpg

Show 7 more facts

Commons category: Multiple sclerosis
NCI Thesaurus ID: C3243
ICPC 2 ID: N86
ICD-9-CM: 340
external data available at URL: www.nanbyou.or.jp/entry/3806
prevalence: 0.001671
exact match: id.nlm.nih.gov/mesh/D009103

Sources (12)

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Article

Multiple sclerosis (MS) is an autoimmune disease where the immune system attacks myelin, the insulating cover of nerve cells in the human body, causing damage to one's own central nervous system. It is a type of demyelinating disease, where the nervous system's ability to transmit signals is damaged. Symptoms can be physical, mental, or both, including double vision, vision loss, eye pain, muscle weakness, loss of sensation and coordination.

MS takes several forms of presentation: