INTS6
Sign in to saveAlso known as DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2, integrator complex subunit 6
Genen från arten Homo sapiens
Gene data
INTS6- Name
- integrator complex subunit 6
- Type
- protein-coding
- Position
- 51,354,077–51,454,264 (−)
- Aliases
- DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, MRD78, Notchl2
- Ensembl
- ENSG00000102786
- RefSeq RNA
- NM_001039937.2, NM_001039938.2, NM_001306091.2, NM_012141.3, XM_011535040.4
- RefSeq protein
- NP_001035026.1, NP_001035027.1, NP_001293020.1, NP_036273.1, XP_011533342.1
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
integrator complex subunit 6
- Symbol
- INTS6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:51,354,077-51,454,264
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8121
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26512
- chromosome
- human chromosome 13
- genomic start
- 51928213
- genomic end
- 52028400
- cytogenetic location
- 13q14.3
Sources (3)
via Wikidata · CC0