INTS6
Sign in to saveAlso known as DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2, integrator complex subunit 6
Integrator complex subunit 6 is a protein that in humans is encoded by the INTS6 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to INTS6, and connects out to PubMed, human chromosome 13 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 13.
Vinony links it to 7 Wikipedia language editions.
Gene data
INTS6- Name
- integrator complex subunit 6
- Type
- protein-coding
- Position
- 51,354,077–51,454,264 (−)
- Aliases
- DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, MRD78, Notchl2
- Ensembl
- ENSG00000102786
- RefSeq RNA
- NM_001039937.2, NM_001039938.2, NM_001306091.2, NM_012141.3, XM_011535040.4
- RefSeq protein
- NP_001035026.1, NP_001035027.1, NP_001293020.1, NP_036273.1, XP_011533342.1
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
integrator complex subunit 6
- Symbol
- INTS6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:51,354,077-51,454,264
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8121
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26512
- chromosome
- human chromosome 13
- genomic start
- 51928213
- genomic end
- 52028400
- cytogenetic location
- 13q14.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Integrator complex subunit 6 is a protein that in humans is encoded by the INTS6 gene.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
Excerpted from Wikipedia’s “INTS6” article, available under the CC BY-SA 4.0 licence.