INTS11
Sign in to saveAlso known as CPSF73L, INT11, RC-68, RC68, CPSF3L, cleavage and polyadenylation specific factor 3-like, integrator complex subunit 11
Integrator complex subunit 11 is a protein that in humans is encoded by the CPSF3L gene.
Gene data
INTS11- Name
- integrator complex subunit 11
- Type
- protein-coding
- Position
- 1,311,585–1,324,687 (−)
- Aliases
- CPSF3L, CPSF73L, INT11, NEDMLOB, PSF3L, RC-68, RC68
- Ensembl
- ENSG00000127054
- RefSeq RNA
- NM_001256456.2, NM_001256460.2, NM_001256462.2, NM_001256463.2, NM_017871.6
- RefSeq protein
- NP_001243385.1, NP_001243389.1, NP_001243391.1, NP_001243392.1, NP_060341.2
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
integrator complex subunit 11
- Symbol
- INTS11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:1,311,585-1,324,688
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9894
- cytogenetic location
- 1p36.33
- exact match
- identifiers.org/ncbigene/54973
- genomic start
- 1246965
- genomic end
- 1324687
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- External links
- Further reading
Integrator complex subunit 11 is a protein that in humans is encoded by the CPSF3L gene.
==References==
Available in 7 languages
via Wikidata sitelinks · CC0