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GeneQ18040510· pop 6· linked from 5 articles

Also known as CPSF-73, CPSF73, cleavage and polyadenylation specific factor 3

Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene.

Gene data

CPSF3
Name
cleavage and polyadenylation specific factor 3
Type
protein-coding
Aliases
CPSF-73, CPSF73, NEDMHS, NEDMHSN

This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing. [provided by RefSeq, Oct 2012].

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Gene · Ensembl

cleavage and polyadenylation specific factor 3

Symbol
CPSF3
Biotype
Protein coding
Organism
Homo sapiens
Location
2:9,423,623-9,473,117
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein CPSF3 PDB 2i7t.png
Show 6 more facts
HomoloGene ID
6499
genomic end
9613230
genomic start
9423651
cytogenetic location
2p25.1
Commons category
Cleavage and polyadenylation specificity factor subunit 3
Sources (4)

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Article

3 sections
Contents
  • References
  • External links
  • Further reading

Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene.

==References==

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