CSTF3
Sign in to saveAlso known as CSTF-77, cleavage stimulation factor subunit 3
Cleavage stimulation factor 77 kDa subunit is a protein that in humans is encoded by the CSTF3 gene.
Gene data
CSTF3- Name
- cleavage stimulation factor subunit 3
- Type
- protein-coding
- Aliases
- CSTF-77
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
cleavage stimulation factor subunit 3
- Symbol
- CSTF3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:33,077,188-33,162,371
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CSTF3 PDB 2ond.png
Show 5 more facts
- HomoloGene ID
- 1014
- exact match
- identifiers.org/ncbigene/1479
- genomic end
- 33183917
- genomic start
- 33098734
- cytogenetic location
- 11p13
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Cleavage stimulation factor 77 kDa subunit is a protein that in humans is encoded by the CSTF3 gene.
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.