CSTF2
Sign in to saveAlso known as CstF-64, cleavage stimulation factor subunit 2
Cleavage stimulation factor 64 kDa subunit is a protein that in humans is encoded by the CSTF2 gene,which is located on the X-chromosome in Homo sapiens, but has an autosomal paralog CSTF2T on chromosome 19 coding for the protein CstF64τ.
Gene data
CSTF2- Name
- cleavage stimulation factor subunit 2
- Type
- protein-coding
- Chromosome
- X
- Aliases
- CSTF64, CstF-64, XLID113
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
cleavage stimulation factor subunit 2
- Symbol
- CSTF2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:100,820,331-100,843,533
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CSTF2 PDB 1p1t.png
Show 5 more facts
- HomoloGene ID
- 80171
- exact match
- identifiers.org/ncbigene/1478
- genomic end
- 100841520
- genomic start
- 100075384
- cytogenetic location
- Xq22.1
Sources (3)
via Wikidata · CC0
~12 min read
Article
15 sectionsContents
- Tissue distribution
- Testes
- Central nervous system
- Immune system
- Structure
- Function
- Spermatogenesis
- Nervous system polyadenylation
- Immunoglobulin class switching
- Overlap between CSTF-64 and CSTF-64τ
- Regulation of alternative polyadenylation
- Interactions
- References
- External links
- Further reading
Cleavage stimulation factor 64 kDa subunit is a protein that in humans is encoded by the CSTF2 gene,which is located on the X-chromosome in Homo sapiens, but has an autosomal paralog CSTF2T on chromosome 19 coding for the protein CstF64τ.
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.