Gene data
CSTF3- Name
- cleavage stimulation factor subunit 3
- Type
- protein-coding
- Position
- 33,077,188–33,162,371 (−)
- Aliases
- CSTF-77
- Ensembl
- ENSG00000176102
- RefSeq RNA
- NM_001033505.2, NM_001033506.2, NM_001326.3
- RefSeq protein
- NP_001028677.1, NP_001028678.1, NP_001317.1
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
mRNA surveillance pathway - Homo sapiens (human)DiseaseInfectious diseasemRNA 3'-end processingProcessing of Capped Intron-Containing Pre-mRNARNA Polymerase II Transcription TerminationRNA Polymerase II TranscriptionGene expression (Transcription)Processing of Capped Intronless Pre-mRNAProcessing of Intronless Pre-mRNAs
via MyGene.info
Gene · Ensembl
cleavage stimulation factor subunit 3
- Symbol
- CSTF3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:33,077,188-33,162,371
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CSTF3 PDB 2ond.png
Show 8 more facts
- HomoloGene ID
- 1014
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1479
- genomic end
- 33183917
- genomic start
- 33098734
- chromosome
- human chromosome 11
- cytogenetic location
- 11p13
- expressed in
- sperm
Sources (3)
via Wikidata · CC0