COPS6
Sign in to saveAlso known as CSN6, MOV34-34KD, COP9 signalosome subunit 6
COP9 signalosome complex subunit 6 is a protein that in humans is encoded by the COPS6 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to COPS6, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Vinony links it to 5 Wikipedia language editions.
Gene data
COPS6- Name
- COP9 signalosome subunit 6
- Type
- protein-coding
- Position
- 100,088,948–100,095,185 (+)
- Aliases
- CSN6, MOV34-34KD
- Ensembl
- ENSG00000168090
- RefSeq RNA
- NM_006833.5
- RefSeq protein
- NP_006824.2
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
COP9 signalosome subunit 6
- Symbol
- COPS6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:100,088,948-100,095,185
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4977
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10980
- genomic end
- 100092187
- genomic start
- 100088969
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
COP9 signalosome complex subunit 6 is a protein that in humans is encoded by the COPS6 gene.
== Function ==
Excerpted from Wikipedia’s “COPS6” article, available under the CC BY-SA 4.0 licence.