GPS1

Also known as COPS1, CSN1, SGN1, G protein pathway suppressor 1

The COP9 signalosome complex subunit 1 is a protein encoded by the GPS1 gene.

Gene data

GPS1

Name: G protein pathway suppressor 1
Type: protein-coding
Position: 82,050,691–82,058,057 (+)
Aliases: COPS1, CSN1, SGN1
Ensembl: ENSG00000169727
RefSeq RNA: NM_001321089.3, NM_001321090.3, NM_001321091.3, NM_001321092.3, NM_001321093.3
RefSeq protein: NP_001308018.1, NP_001308019.1, NP_001308020.1, NP_001308021.1, NP_001308022.1

This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. [provided by RefSeq, Mar 2016].

Gene Ontology

Biological process

protein deneddylation JNK cascade

Article

2 sections

Contents

References
Further reading

The COP9 signalosome complex subunit 1 is a protein encoded by the GPS1 gene.

This gene is known to inhibit G-protein and mitogen-activated signal transduction in mammalian cells. The protein encoded by this gene shares significant similarity with Arabidopsis FUS6, a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.