IPO8
Sign in to saveAlso known as RANBP8, importin 8, VISS
Importin 8 is a protein that in humans is encoded by the IPO8 gene.
Gene data
IPO8- Name
- importin 8
- Type
- protein-coding
- Position
- 30,628,981–30,695,883 (−)
- Aliases
- RANBP8, VISS
- Ensembl
- ENSG00000133704
- RefSeq RNA
- NM_001190995.2, NM_006390.4, XM_017018691.3, XM_017018692.2, XM_017018693.3
- RefSeq protein
- NP_001177924.1, NP_006381.2, XP_016874180.1, XP_016874181.1, XP_016874182.1
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
importin 8
- Symbol
- IPO8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:30,628,981-30,695,908
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 48430
- exact match
- identifiers.org/ncbigene/10526
- genomic end
- 30695869
- genomic start
- 30781922
- cytogenetic location
- 12p11.21
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Importin 8 is a protein that in humans is encoded by the IPO8 gene.
== Function ==