IPO8
Sign in to saveAlso known as RANBP8, importin 8, VISS
Importin 8 is a protein that in humans is encoded by the IPO8 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to IPO8, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Vinony links it to 5 Wikipedia language editions.
Gene data
IPO8- Name
- importin 8
- Type
- protein-coding
- Position
- 30,628,981–30,695,908 (−)
- Aliases
- RANBP8, VISS
- Ensembl
- ENSG00000133704
- RefSeq RNA
- NM_001190995.2, NM_006390.4, XM_017018691.3, XM_017018692.2, XM_017018693.3
- RefSeq protein
- NP_001177924.1, NP_006381.2, XP_016874180.1, XP_016874181.1, XP_016874182.1
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
importin 8
- Symbol
- IPO8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:30,628,981-30,695,908
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 48430
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10526
- genomic end
- 30695869
- genomic start
- 30781922
- chromosome
- human chromosome 12
- cytogenetic location
- 12p11.21
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Importin 8 is a protein that in humans is encoded by the IPO8 gene.
== Function ==
Excerpted from Wikipedia’s “IPO8” article, available under the CC BY-SA 4.0 licence.