ISL1
Sign in to saveAlso known as ISLET1, Isl-1, ISL LIM homeobox 1
Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the ISL1 gene.
Gene data
ISL1- Name
- ISL LIM homeobox 1
- Type
- protein-coding
- Aliases
- ISLET1, Isl-1
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein ISL1 PDB 1bw5.png
Show 6 more facts
- HomoloGene ID
- 1661
- genomic start
- 50678921
- exact match
- identifiers.org/ncbigene/3670
- genomic end
- 51394730
- cytogenetic location
- 5q11.1
- Commons category
- Insulin gene enhancer protein isl-1
Sources (3)
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Function
- Interactions
- Role in cardiac development
- References
- Further reading
- External links
Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the ISL1 gene.
== Function ==