isocarboxazid
Sign in to saveIsocarboxazid, sold under the brand name Marplan among others, is a non-selective irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class used as an antidepressant. Along with phenelzine and tranylcypromine, it is one of only three classical MAOIs still available for clinical use in the treatment of psychiatric disorders in the United States, though it is not as commonly employed in comparison to the others.
Research
437 papersvia PubMed
Wikidata facts
- Mass
- 231.100777
Show 5 more facts
- chemical formula
- C₁₂H₁₃N₃O₂
- World Health Organisation international non-proprietary name
- isocarboxazid
- canonical SMILES
- CC1=CC(=NO1)C(=O)NNCC2=CC=CC=C2
- defined daily dose
- 15
- Commons category
- Isocarboxazid
via Wikidata · CC0
~2 min read
Article
3 sectionsContents
- Contraindications
- See also
- References
Isocarboxazid, sold under the brand name Marplan among others, is a non-selective irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class used as an antidepressant. Along with phenelzine and tranylcypromine, it is one of only three classical MAOIs still available for clinical use in the treatment of psychiatric disorders in the United States, though it is not as commonly employed in comparison to the others.
Isocarboxazid is primarily used to treat mood and anxiety disorders. It has also been investigated in the treatment of schizophrenia, Parkinson's disease, and other dementia-related disorders.