JCHAIN
Sign in to saveAlso known as IGCJ, JCH, IGJ, J chain, joining chain of multimeric IgA and IgM
protein-coding gene in the species Homo sapiens
Gene data
JCHAIN- Name
- joining chain of multimeric IgA and IgM
- Type
- protein-coding
- Position
- 70,655,541–70,681,817 (−)
- Aliases
- IGCJ, IGJ, JCH
- Ensembl
- ENSG00000132465
- RefSeq RNA
- NM_144646.4, XM_054349952.1, XM_054349953.1, XM_054349954.1, XM_054349955.1
- RefSeq protein
- NP_653247.1, XP_054205927.1, XP_054205928.1, XP_054205929.1, XP_054205930.1
Enables IgA binding activity and protein homodimerization activity. Contributes to several functions, including immunoglobulin receptor binding activity; peptidoglycan binding activity; and phosphatidylcholine binding activity. Involved in several processes, including defense response to other organism; glomerular filtration; and positive regulation of respiratory burst. Located in extracellular space. Part of monomeric IgA immunoglobulin complex; pentameric IgM immunoglobulin complex; and secretory dimeric IgA immunoglobulin complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
joining chain of multimeric IgA and IgM
- Symbol
- JCHAIN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:70,652,871-70,681,817
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 16958
- exact match
- identifiers.org/ncbigene/3512
- genomic end
- 71547534
- genomic start
- 71521258
- cytogenetic location
- 4q13.3
via Wikidata · CC0