PIGR
Sign in to saveAlso known as polymeric immunoglobulin receptor
protein-coding gene in the species Homo sapiens
Gene data
PIGR- Name
- polymeric immunoglobulin receptor
- Type
- protein-coding
- Position
- 206,928,522–206,949,367 (−)
- Ensembl
- ENSG00000162896
- RefSeq RNA
- NM_002644.4, XM_011509629.2, XM_054337031.1
- RefSeq protein
- NP_002635.2, XP_011507931.1, XP_054193006.1
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
detection of chemical stimulus involved in sensory perception of bitter tasteimmunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptorimmunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptorsignal transductionepidermal growth factor receptor signaling pathwayFc receptor signaling pathwayreceptor clustering
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
polymeric immunoglobulin receptor
- Symbol
- PIGR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:206,928,522-206,949,367
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PIGR PDB 1xed.png
Show 8 more facts
- HomoloGene ID
- 1984
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5284
- genomic end
- 207119811
- genomic start
- 206928522
- chromosome
- human chromosome 1
- cytogenetic location
- 1q32.1
- Commons category
- Polymeric immunoglobulin receptor
via Wikidata · CC0