JPH1
Sign in to saveAlso known as JP-1, JP1, CMT2K, junctophilin 1
Junctophilin-1 is a protein that in humans is encoded by the JPH1 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to JPH1, and connects out to PubMed, human chromosome 8 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 8.
Vinony links it to 5 Wikipedia language editions.
Gene data
JPH1- Name
- junctophilin 1
- Type
- protein-coding
- Position
- 74,234,700–74,321,607 (−)
- Aliases
- CMT2K, CMYO25, JP-1, JP1
- Ensembl
- ENSG00000104369
- RefSeq RNA
- NM_001317830.2, NM_001363050.1, NM_001363051.1, NM_020647.4, XM_047421996.1
- RefSeq protein
- NP_001304759.1, NP_001349979.1, NP_001349980.1, NP_065698.1, XP_047277952.1
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
junctophilin 1
- Symbol
- JPH1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:74,234,700-74,321,607
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 10761
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/56704
- genomic end
- 74321540
- genomic start
- 75146935
- chromosome
- human chromosome 8
- cytogenetic location
- 8q21.11
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Junctophilin-1 is a protein that in humans is encoded by the JPH1 gene.
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.
Excerpted from Wikipedia’s “JPH1” article, available under the CC BY-SA 4.0 licence.