KATNB1
Sign in to saveAlso known as KAT, LIS6, katanin regulatory subunit B1
Gen der Spezies Homo sapiens
Gene data
KATNB1- Name
- katanin regulatory subunit B1
- Type
- protein-coding
- Position
- 57,735,669–57,758,271 (+)
- Aliases
- KAT, LIS6
- Ensembl
- ENSG00000140854
- RefSeq RNA
- NM_005886.3
- RefSeq protein
- NP_005877.2
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
protein targetingmicrotubule depolymerizationnegative regulation of microtubule depolymerizationmitotic chromosome movement towards spindle polepositive regulation of neuron projection developmentpositive regulation of microtubule depolymerizationpositive regulation of microtubule depolymerizationcytoplasmic microtubule organization
Molecular function
via MyGene.info
Gene · Ensembl
katanin regulatory subunit B1
- Symbol
- KATNB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:57,735,669-57,758,271
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 4302
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10300
- chromosome
- human chromosome 16
- genomic start
- 57735739
- genomic end
- 57757244
- cytogenetic location
- 16q21
- genetic association
- lissencephaly
- expressed in
- Brodmann area 10
via Wikidata · CC0