KATNB1
Sign in to saveAlso known as KAT, LIS6, katanin regulatory subunit B1
Katanin p80 WD40-containing subunit B1 is a protein that in humans is encoded by the KATNB1 gene.
In the Vinony graph
Within Vinony's link graph, KATNB1 is referenced by 7 other articles, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 16.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KATNB1- Name
- katanin regulatory subunit B1
- Type
- protein-coding
- Position
- 57,735,669–57,758,271 (+)
- Aliases
- KAT, LIS6
- Ensembl
- ENSG00000140854
- RefSeq RNA
- NM_005886.3
- RefSeq protein
- NP_005877.2
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
katanin regulatory subunit B1
- Symbol
- KATNB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:57,735,669-57,758,271
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 4302
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10300
- chromosome
- human chromosome 16
- genomic start
- 57735739
- genomic end
- 57757244
- cytogenetic location
- 16q21
- genetic association
- lissencephaly
- expressed in
- Brodmann area 10
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Katanin p80 WD40-containing subunit B1 is a protein that in humans is encoded by the KATNB1 gene.
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. KATNB1 is associated with microlissencephaly.
Excerpted from Wikipedia’s “KATNB1” article, available under the CC BY-SA 4.0 licence.